The ICOSLG Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to ICOSLG. This antibody recognizes Human antigen. The ICOSLG Antibody has been validated for the following applications: ELISA, and Western Blot.
Description
Function: Ligand for the T-cell-specific cell surface receptor ICOS. Acts as a costimulatory signal for T-cell proliferation and cytokine secretion; induces also B-cell proliferation and differentiation into plasma cells. Could play an important role in mediating local tissue responses to inflammatory conditions, as well as in modulating the secondary immune response by co-stimulating memory T-cell function (By similarity).
Subunit Structure: Interacts with CTLA4 (in vitro).
Similarity: Belongs to the immunoglobulin superfamily. BTN/MOG family